Coronavirus Vaccine Trial in Wuhan Has Proven Successful According to Peer-Reviewed Lancet Report

 -  -  22


A peer-reviewed report points to the success of initial trials on humans test subjects in Wuhan of a Novel Coronavirus vaccine.

On 16 March the first stage of clin­i­cal tri­als of a COVID-19 re­com­bi­nant vac­cine com­menced in the Hubei-province cap­i­tal of Wuhan where the dis­ease first emerged. 

The vac­cine was de­vel­oped by a team led by epi­demi­ol­o­gist Chen Wei (陈薇) from the Acad­emy of Mil­i­tary Med­ical Sci­ences, with the in­volve­ment of Hong Kong-listed CanSino Bio-B. 

A peer-reviewed report published by The Lancet now points to the initial success of the trial.

“This first-in-human trial showed that the Ad5 vectored COVID-19 vaccine was tolerable and immunogenic in healthy adults,” said the report.

“Humoral responses against SARS-CoV-2 peaked at day 28 post-vaccination in healthy adults, and rapid specific T-cell responses were noted from day 14 post-vaccination.

“One dose of the vaccine at all dose concentrations (5 × 1010, 1 × 1011, and 1·5 × 1011 viral particles) tested induced both specific antibody and T-cell responses in most participants. Rapid specific T-cell responses were noted at day 14 and specific humoral responses against severe acute respiratory syndrome coronavirus 2 peaked at day 28 post-vaccination. “

The trial involves a to­tal of 108 trial par­tic­i­pants, with a re­search and ob­ser­va­tion pe­riod of at least six months. 

China recently completed work on the world’s largest vaccine plant with an annual capacity of 100 million doses. The plant will be dedicated to the production of COVID-19 vaccines.

Related stories

China Builds World’s Biggest Vac­cine Plant,100 Mil­lion Dose Ca­pac­ity to Be Used for COVID-19 Vac­cine

China Sheds Light on Se­lec­tion Process for COVID-19 Vac­cine Vol­un­teers, Says Prod­uct Could be Ready by Sep­tem­ber

108 Vol­un­teers Sign up for Stage 1 COVID-19 Vac­cine Tri­als in Wuhan Held by CanSino Bio-B

2 recommended
comments icon 2 comments
2 notes
294 views
bookmark icon

Write a comment...

Your email address will not be published. Required fields are marked *